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Early-life exposure to allergens triggers a distinct local mode of dendritic cell activation in neonatal skin without requiring migration to lymph nodes, which shapes responses to allergens in later life.
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SSIM was chosen over CNN-based approaches for a deliberate reason: reproducibility without infrastructure. SSIM is a deterministic mathematical function. No training data, no model weights, no GPU, no framework dependencies. Anyone with fontconfig and node-canvas can reproduce these exact numbers on the same platform.
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